Synthetic Nootropics

Tianeptine Sodium: Benefits, Dosing, Side Effects, And More!

Typical daily doses range from 12.5 mg to 37.5 mg
Russian/Soviet CompoundsSerotonergics
Erik Abramowitz, FNTP
Reviewed by Erik Abramowitz, FNTP Last updated February 5, 2026
Regulatory Warning: This substance is subject to active FDA enforcement action, has been involved in federal criminal prosecutions, or is classified as unsafe for sale as a dietary supplement. This page is retained for educational and harm-reduction purposes only. Do not purchase or consume this substance based on information found here.

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Overview

Tianeptine Sodium is a synthetic compound primarily used as an antidepressant and anxiolytic. It is known for its unique mechanism of action that enhances mood and cognitive function, making it a subject of interest in nootropic research.

Dosage

Typical daily doses range from 12.5 mg to 37.5 mg, often taken in divided doses throughout the day. It is generally recommended to take Tianeptine Sodium on an empty stomach for optimal absorption.

Research & Studies

This section includes 2 peer-reviewed studies referenced in our analysis.

Tianeptine Sodium: A Nootropic With Potentially Lethal Consequences.

2018DOI: 10.4088/PCC.17l02205
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Effects of Tianeptine Treatment on Depression and Cognitive Function in Patients with Alzheimer's Disease: A 12-Month Retrospective Observational Study.

2022DOI: 10.3233/JAD-215630
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Medical Disclaimer: This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare provider before starting any supplement regimen.
Reference ID: 1973 Updated: Feb 5, 2026