# Phenibut

- **Canonical URL:** https://holisticnootropics.com/substances/phenibut/
- **Content type:** substance
- **Classification:** GABAergics, Synthetic Nootropics, Russian/Soviet Compounds
- **Risk tier:** Red (Research Use Only — not marketed for human consumption)
- **Typical dosage (published literature):** The typical dosage range for Phenibut is between 250 mg to 1500 mg per day, often taken in divided doses. It is recommended to take it on an empty stomach for optimal absorption, and users should be c
- **Research level:** Moderate
- **Last updated:** 2026-02-05

> **Research Use Only.** This compound is not approved as a dietary supplement. Holistic Nootropics does not recommend or market it for human consumption. Information is provided for research and educational context.

Phenibut is a synthetic derivative of the neurotransmitter GABA (gamma-aminobutyric acid). It is primarily used for its anxiolytic and nootropic effects, promoting relaxation, reducing anxiety, and en

## Overview

Phenibut is a synthetic derivative of the neurotransmitter GABA (gamma-aminobutyric acid). It is primarily used for its anxiolytic and nootropic effects, promoting relaxation, reducing anxiety, and enhancing cognitive function.

## Dosage

The typical dosage range for Phenibut is between 250 mg to 1500 mg per day, often taken in divided doses. It is recommended to take it on an empty stomach for optimal absorption, and users should be cautious of tolerance and potential withdrawal effects with prolonged use.

---

Source: https://holisticnootropics.com/substances/phenibut/
Publisher: Holistic Nootropics (https://holisticnootropics.com) — evidence-based nootropic guides. Affiliate links may appear on the HTML version; see https://holisticnootropics.com/affiliate-disclosure/.