# Holistic Nootropics

> Evidence-based guides to nootropics, cognitive enhancement compounds, and brain-health supplements. Substance monographs cover mechanism of action, clinical data, dosage, safety profile, and vendor sourcing for research use.

Coverage spans three tiers: compliant botanical/nutrient supplements (adaptogens, mushrooms, cholinergics, amino acids), grey-market research chemicals (racetams, bromantane, 9-Me-BC, peptides), and emerging compounds. Every substance page includes peer-reviewed citations, dosage ranges grounded in published research, and explicit Research Use Only framing where appropriate.

## Key pages

- [Substances](https://holisticnootropics.com/substances/): Full substance index — monographs with mechanism, dosage, safety, and research citations
- [Articles](https://holisticnootropics.com/articles/): Long-form guides on stacks, conditions (focus, anxiety, sleep, memory), and comparisons
- [Podcasts](https://holisticnootropics.com/podcasts/): Interviews with researchers, clinicians, and practitioners
- [Search](https://holisticnootropics.com/search/): Fuse.js-powered search across substances, articles, and podcasts

## Popular substance monographs

- [Bromantane (Ladasten)](https://holisticnootropics.com/substances/bromantane/): Russian actoprotector; dopamine synthesis upregulator; 728-patient clinical trial data
- [Flmodafinil (CRL-40,940)](https://holisticnootropics.com/substances/flmodafinil/): Fluorinated modafinil analog; preclinical pharmacology
- [Phenylpiracetam](https://holisticnootropics.com/substances/phenylpiracetam/): Phenyl-substituted racetam; dopamine/norepinephrine modulation
- [Adrafinil](https://holisticnootropics.com/substances/adrafinil/): Modafinil prodrug; eugeroic; liver metabolism considerations
- [9-Methyl-β-carboline](https://holisticnootropics.com/substances/9-methyl-carboline/): MAO-B inhibitor; dopaminergic neuroprotection
- [Noopept](https://holisticnootropics.com/substances/noopept/): Dipeptide nootropic; BDNF/NGF upregulation
- [Lion's Mane](https://holisticnootropics.com/substances/lions-mane/): Hericium erinaceus; NGF stimulation; neurogenesis
- [Alpha-GPC](https://holisticnootropics.com/substances/alpha-gpc/): Cholinergic precursor; acute cognitive performance

## Editorial standards

- Citations drawn from PubMed-indexed journals; primary sources preferred
- Dosage ranges reflect published clinical or preclinical literature, not anecdotal forums
- Risk tiers (Red/Grey/Green) govern content framing; Red/Grey pages include RUO disclaimers and do not market compounds for human consumption
- Affiliate relationships disclosed per FTC requirements on every relevant page
- Content compliant with FDA structure/function claim guidance: no disease treatment claims